Cell Cycle of Spermatogonia in Mouse Testis
نویسندگان
چکیده
منابع مشابه
Autoradiographic Study of Dna Synthesis and the Cell Cycle in Spermatogonia and Spermatocytes of Mouse Testis Using Tritiated Thymidine
Mice were injected intraperitoneally with 15 microc of H(3)-thymidine. The time course of the labeling in spermatogonia and spermatocytes was studied by using autoradiography on 5 micro sections stained by the periodic acid-Schiff method and hematoxylin over a period of 57 hours after injection. Four generations of type A (called AI, AII, AIII, and AIV), one of intermediate, and one of type B s...
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Vitamin A (retinol) is required for maintenance of adult mammalian spermatogenesis. In adult rodents, vitamin A withdrawal is followed by a loss of differentiated germ cells within the seminiferous epithelium and disrupted spermatogenesis that can be restored by vitamin A replacement. However, whether vitamin A plays a role in the differentiation and meiotic initiation of germ cells during the ...
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Spermatogonial stem cells (SSCs) fuel the production of male germ cells but the mechanisms behind SSC self-renewal, proliferation, and differentiation are still poorly understood. Using the Wnt target gene Axin2 and genetic lineage-tracing experiments, we found that undifferentiated spermatogonia, comprising SSCs and transit amplifying progenitor cells, respond to Wnt/β-catenin signals. Genetic...
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BACKGROUND In vitro culture of spermatogonial stem cells (SSCs) is important for exploration of SSCs self-renewal, differentiation, and manipulation. There are several reports on rodent SSC cultures; however, data on SSC cultures in domestic animals are limited. To provide basic scientific information on canine SSC cultures, we report canine testes development, and the development of spermatogo...
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ژورنال
عنوان ژورنال: Investigative Radiology
سال: 1979
ISSN: 0020-9996
DOI: 10.1097/00004424-197903000-00015